blah

9/21/2010 2:46:56 PM

i got cody a present recently

9/21/2010 2:47:23 PM

its pretty badass. should be coming in the mail really soon.

9/21/2010 2:48:04 PM

i wish i could make a thread about it when it comes

9/21/2010 2:48:31 PM

but alas, im not sure my post count will be where it should be

9/21/2010 2:49:15 PM

maybe ill luck out

9/21/2010 2:49:53 PM

im getting close to under 200 !

9/21/2010 2:50:19 PM

im about to postr everything ive memorized int he past few minutes in here

9/21/2010 2:52:20 PM

gimme about 5 min

9/21/2010 2:53:00 PM

im gonna look at the front of the notecard and then just type everything i know.
these are actually really easy, but im not good as memorizing stuff :/.

1. methylation.
enzyme: methyl transferase
cofactor: s-adensylmethionine
transfers a methyl group onto catechols, amines, thiols.
doesnt improve solubility but may disrupt pharmacophore.

9/21/2010 2:58:33 PM

YAY. right

2. sulfation
e: sulfotransferase
cofactor: 3'phosphoadenosine, 5'-phosphosulfate
adds a sulfate to phenols, alcohols, N-hydroxyls, and something else.....





looking:
ARYLAMINES

9/21/2010 3:00:40 PM

by the way all of these are phase ii reactions

3. glucuronidation

e: glucuronosyl transferase
cf: uridine diphosphate glucoronic acid
transfers a glucoronic acid to a alcohol, phenol, aryl amine, and other stuff (SHIT)

looking:

SULFAHYDRYLS
AROMATIC CARBOXYLIC ACIDS

9/21/2010 3:03:29 PM

glutathione conjugation:
a. glutathione transferase
cf: glutathione

transfers a glutathione to SHIT. i dont remember. i do know that glutathione has a sulfer in it.
im gonna guess:
epoxides, halides, and other electrophiles

9/21/2010 3:05:29 PM

DING DING

4. amino acid conjugation
e: acyl synthetase
cf. coenzyme A and glycine or glutamine

conjugates an amino acid to carboxyilic acids.
this is one im gonna have to look up b/c im not sure if its any amino acid or if its either glycine or glutamine. common sense tells me its the latter.

9/21/2010 3:07:36 PM

this thread is kinda making me happy that the PCAT handed me my ass.

not looking forward to any of this should i ever get into pharm school

9/21/2010 3:11:30 PM

last one!!!


acetylation
acetyl transferase
acetyl coa

transfers acetyl coa to amino acids, aromaic amines, hydrazines, sulfonamides!

9/21/2010 3:12:04 PM

^^its really not that bad. its just A LOT.

9/21/2010 3:12:26 PM

eeeeech. cyp450 is a busy little bee

9/21/2010 3:23:16 PM

im soooooo hungryyyyyy

9/21/2010 3:45:02 PM

I hope you got some food, Joie. You were starting to sound like a monster.

9/21/2010 8:10:39 PM

9/21/2010 8:13:03 PM

^^i did

9/21/2010 8:14:54 PM

9/21/2010 8:15:29 PM

meatballs

9/21/2010 8:19:10 PM

grapes

9/21/2010 8:19:32 PM

cheese cubes

9/21/2010 8:20:12 PM

veggies and ranch

9/21/2010 8:20:46 PM

i went to a bank chairman retirement reception

9/21/2010 8:21:14 PM

we're meeting with the potential wedding coordinator tomorrow

9/21/2010 8:22:18 PM

im gonna finish up some of my look book

9/21/2010 8:22:40 PM

and then study

9/21/2010 8:25:26 PM

lol this is effing hysterical

9/21/2010 8:50:09 PM

204 more to go man.

9/21/2010 8:51:45 PM

U CAN DO IT!

9/21/2010 8:52:30 PM

oh i will

9/21/2010 8:52:58 PM

9/21/2010 8:53:25 PM

9/21/2010 8:53:32 PM

you better you betta you bet

9/21/2010 8:53:35 PM

done for the night

9/21/2010 8:53:57 PM

done with what

9/21/2010 8:54:20 PM

hahaha



thank you kiwi!!

9/21/2010 8:58:31 PM

^^i meant i was done posting...until i saw that

9/21/2010 8:59:09 PM

lol

9/21/2010 8:59:43 PM

alright im really gonna study now

9/21/2010 9:00:11 PM

why be done

get it over with

get 200 TONIIIIGHT LOL

9/21/2010 9:00:15 PM

i have too much studying

9/21/2010 9:02:47 PM

and i gotta be up early

9/21/2010 9:03:25 PM

see yall tomorrow


ps. i also find it funny that not many people realize im doing this

9/21/2010 9:04:01 PM

I didn't lol. I looked at your posts and it goes back like 13 pages or some shit of just this thread. lol

9/21/2010 9:05:34 PM

9/21/2010 9:09:10 PM