7

10/13/2010 9:35:59 PM

holy shit.

test average was a low D.

im not nearly as upset about my F anymore (at least it was a high one)

10/14/2010 11:07:34 AM

i dropped my first grad course about a week ago if it makes you feel better

10/14/2010 11:10:51 AM

lemme tell you about the heart conduction system

the SA node is the pace maker. it generates an electric signal that is sent down the atrial body and is brought back together at the AV node. here, the signal is slowed down a bit and then conducted to the bundle branches, perjunke his, and then finally the ventricular myocardium.

SNS nerves innervate the whole heart while PNS only really SA and AV node (small bit on atrial body).

Next installment:how in the world does the electrical signal generate?

11/16/2010 4:07:54 PM

SOOOOOO the AV node.
first lets discuss the cell. it has high Na outside, high K inside, and high Ca outside. these are impermeable to the cell membrane. however there are channels that transport them.
the Na/K/ATPase is an energy driven one that keeps the concentration of potassium ions high in the cell.
Then of course there are NA, K, and Ca channels that are either regulated or open.

K is the most important for right now. it has channels all along the membrane and at any given time some are open and some are closed. now you may ask yourself. if the concentration of K is so high inside of the cell and so low outside of the cell why doesn;t the K rush out? well keep in mind there is a huge amount of Na AND Ca outside of the cell. all of the ions have a positive chrarge, meaning that there is MUCH more positive charges outside of the cell and the K is kept inside the cell where it is nice and negative (about 90 millivolts).

in the SA node there are these "leaky channels" that let Na in (now Na will be flowing in towards the lower concentration AND negative charge) . as the Na lets in the negative potential inside the cell slowly gets more positive and positive until it reaches a threshold (about 40 milivolts)

when this threshold is hit Ca channels (L type-voltage dependent) open. and calcium floods into the cell. the positive volatage will signal the myocardial cells to open their (voltage regulated) Na channels and BAM. you have electrical current.


How does the SA node repolarize?

[Edited on November 16, 2010 at 4:22 PM. Reason : im doing this with little help as possible ]

11/16/2010 4:21:55 PM

once the cell reaches a certain depolarization point (about +70) the calcium channels become inactivated. this means that calcium cannot flow in. at this time potassium channels open and K is allowed to rushes out, leaving the cell back at its -90 membrane potential.

[Edited on November 16, 2010 at 4:34 PM. Reason : actually im not sure is K rushes out. i just emailed my professor ]

11/16/2010 4:32:00 PM

i got 56 for my hospital rotations.



should i take a december rotation (thats gonna be jam packed and probably a little stressful)
or should i take it in july? (this would be before my top 300 test....which studying for it is gonna be really relly stressful)

11/20/2010 11:38:29 AM

December.

11/20/2010 2:19:15 PM

oh word, you're learning about action potentials and synapses? that's what i did in my class earlier this year

[Edited on November 20, 2010 at 2:23 PM. Reason : though Ca doesn't really matter until the ap hits the synaptic cleft (other than charge balancing)]

11/20/2010 2:21:23 PM

actually we did action potentials in general last year.


right now we are focusing on the heart (which as ou know is pretty different from the brain or muscle!)

[Edited on November 20, 2010 at 2:26 PM. Reason : im leaning toward dec too]

11/20/2010 2:25:53 PM

aww focusing on the heart is what i always do lol

11/20/2010 2:27:33 PM

oic

i just went over that crap thursday actually, very quickly before we start going over pacemakers

weirdly similar

11/20/2010 2:27:48 PM

GREAT

i found out today that there are 118 spots open for hospital rotations, about 20 availiable in the raleigh-cary-durham area.



i drew number 56.


i think im screwed

11/22/2010 12:08:46 PM

You should have ripped off the 6

11/22/2010 12:16:32 PM

they were written on poker chips

11/22/2010 12:19:02 PM

we talked about pharmacogenomics the other day and I thought of youuuu

11/22/2010 12:19:36 PM

How will you find out where you get assigned?

11/22/2010 12:20:01 PM

we've only talked about it in detail like twice, but we keep referencing it ^i

[Edited on November 22, 2010 at 12:21 PM. Reason : ^i get to pick from a list....but im number 56 ]

11/22/2010 12:21:02 PM

I hope everyone picks something closer to campus and that way you have a better shot at getting something around here.

11/22/2010 12:24:22 PM

holy crap.

so one of my grades in a certain class have been really bad.
my 1st two tests were both a 60 and i started to freak out.
(i dont care about making a bad grade on one test but two in a row?? somethings wrong)
however i made an 85 on the 3rd one and was BESIDE myself for like a week.

i took my 4th one today and was SURE i had secured my D for this semester.


I MADE AN 82!!!

now i f i can just do ok on the final!



[Edited on November 23, 2010 at 6:34 PM. Reason : rerfes]

11/23/2010 6:26:25 PM

SEE I TOLD YOU!!!!

yayyyyy

11/23/2010 6:56:10 PM

SAMWISE

i thought of you

11/23/2010 7:33:29 PM

OH FUCK NO

11/23/2010 7:34:56 PM

^thats what i said

11/23/2010 7:37:48 PM

i would scream like chris tucker if i saw that irl

11/23/2010 7:41:43 PM

i peed myself a little watching it.

11/23/2010 7:48:03 PM

you're gross

11/23/2010 7:48:33 PM

That was awesome

11/24/2010 4:16:42 AM

man oh man.

i didnt get to sleep last night

and my kinetics exam is in about 1.5 hours, but my pharmacology exam is effing tomorrow morning.


i hope to god and all that is holy i can take a power nap this afternoon, or at least sleep tonight (my lack of sleep is 100% due to stress )

im starting to get tired though.
thats a good sign

11/29/2010 7:31:10 AM

good luck joice!

and Melatonin seems to work well for me.

11/29/2010 7:37:47 AM

i dont have any (with me) and getting some is probably not gonna happen (im in buies creek staying with a friend )


on a lighter note......i have to make an 80% on this exam to make an A in this class, and a 5% to make a D ;-) (i hope i calculated that right!)

on the downside-its only 2 credits

[Edited on November 29, 2010 at 7:51 AM. Reason : kfsdla]

11/29/2010 7:51:12 AM

lol then save your luck for later... but it has still been wished upon you.


and i used to go to buies creek all the time to camp when i was a kid

[Edited on November 29, 2010 at 7:55 AM. Reason : .]

11/29/2010 7:54:12 AM

campbell university?

11/29/2010 7:57:53 AM

one down. 3 to go.

my nasty one is tomorrow and im really worried i havent gotten any sleep

i took 2.5x my normal clonazepam to keep my mind form going 100 miles a minute (i'm on a low dosage plus it has a high therapeutic index, so dont worry, no od-ing over here )


im gonna lie down. maybe listento some music and try to power nap for about 3 hours.

that sound like a plan to yall?
i dont wanna push it through until tongiht cause i feel like i wont get quality of studying done....

11/29/2010 11:47:40 AM

can I join your thread?

I'm so sick of going through countless acronyms and gene names and recurrence risks

11/30/2010 6:57:28 PM

it'd be pretty funny if you ODed while studying for a pharmacy test

a sad funny, but still

11/30/2010 6:59:46 PM

^^come on in!!!!


on my last test we had a series of questions asking things like....

a patient has an allergy attack, shes has been studying all week and is very tired and would like to go to sleep, what should you reccommend?...

or

which med is the most efficacious for GERD?...

and we had a "word bank"

the thing is...there were no words IT WAS ALL CHEMICAL STRUCTURES >.<

11/30/2010 7:21:26 PM

so for my exam tomorrow. if i make a 68 i get an 80, if i make a 100 i get an 87.
combine that with the fact that we don't get partial gpa's (ie 90-100 is 4.0, 80-89 is 3.0 etc etc)

im aiming low tomorrow.

12/2/2010 2:34:35 PM

Hello Joie,

I heard that you has nude pics on the internet. Can you please point me to them? any PM'd links will be held in respectful confidence.

Thanks in advance for your attention to this rather pressing need.

12/2/2010 2:41:14 PM

Lol

Joice , I didn't mean like summer camp I meant like sleeping in a tent in the middle of nowhere :-). I had a friend with some land out there and we used to camp on "the back 50(acres)"

12/2/2010 2:57:23 PM

last exam in an hour and fifteen!!!!!!!!!!!!!!!!!

12/3/2010 7:44:39 AM

good luck!

12/3/2010 7:58:30 AM

DMD involves a loss of ambulation by 13 years old, BMD involves a loss of ambulation by 16 years old... x-linked, DMN (dystrophin) gene.. big calves, gower, develop contractures and usually die from pulmonary or cardiac complications

SMA 0 is present from birth and fatal
SMA I presents by 6 mths old with severe hypotonia, typically won't live past 2 y/o... tongue fasciculations key finding
SMA II presents after 6 mths old and they will at least be able to sit up later in life
SMA III presents 18 months and later.. can walk and stand at some point... normal life expectancy
SMA IV less severe, with muscle weakness.. normal life expectancy... gynecomastia and testicular atrophy noted
SMA 0-III are autosomal recessive (SMN1/2) and SMA IV is X-linked recessive (UBA1) w/ a CAG repeat (anticipation also noted)
SMA is the 2nd most common autosomal recessive disorder (following CF)

Myotonic Dystrophy is autosomal dominant.. Type I includes a congenital form which has severe hypotonia, facial weakness, and feeding/breathing difficulties... reg type I involves myotonia, arrhythmias, intellectual disability, cataracts, obstructive sleep apnea, and cardiomyopathy... Type I also due to a CTG repeat and anticipation is seen.
Type II does not have a congenital form and involves weakness, exercise intolerance, and hyperhidrosis... involves CCTG or TCTG repeat (no anticipation)


Hereditary spastic paraparesis has two forms, pure (leg weakness only) and complicated (leg weakness + other systems involved). Can be caused by autosomal dominant (SPG4), autosomal recessive (SPG20), or x-linked recessive (SPG1).

Amyotrophic Lateral Sclerosis involves widespread degeneration of upper and lower motor neurons, no reflexes, ataxia, fasciculations, and muscular atrophy.... can be inherited through autosomal dominant, autosomal recessive, and x-linked inheritance

Friedreich Ataxia involves ataxia (duh), dysphagia, bladder complications, diabetes and cardiomyopathy... autosomal recessive, FXN gene.. due to a GAA repeat



fuck this test

12/7/2010 1:17:27 AM

Genetics in Medicine final at 2:30 now to review over 100 syndromes


I don't understand why they put a bridge right next to the health professions library... >_>

[Edited on December 8, 2010 at 10:05 AM. Reason : .]

12/8/2010 10:04:53 AM

ugh

I have a final tomorrow and I don't care anymore.

this suuuuuuucks.

12/9/2010 3:37:29 AM

for a post tensioned continuous indeterminate beam we have two moment profiles we must consider. One from the eccentricity of the tendon and the other from the mid span support. The primary moment follows the profile of the tendon ( as we should all know by now ). The secondary moment is caused by the mid-span support.

In order to calculate the final moment for this indeterminate beam we must consider both profiles and superimposed its deflections. In this case we will use the moment-area method in which we will calculate the deflection for the primary moment and then the secondary moment. The secondary moment will contain an unknown reaction ( as this is the nature of the indeterminate beam), but is found when we equate the secondary moment to the primary moment. Thus with the reaction found we can find the values for the secondary moment.

With all values we superimpose the moments and find the final moment. With this final moment we can find the thrust C-line. The C-line is where the prestress force is felt in the beam and not the actual physical location of the prestress.

12/9/2010 3:49:00 AM

^i understood that, and yet am completely lost

(ie i understand the words but not conceptually)



have fun with that

[Edited on December 9, 2010 at 9:17 AM. Reason : i read it like 4 times]

12/9/2010 9:17:22 AM

Bio med engineer I'm guessing? I understand the concepts and some of the words but had to look some up lol.

12/9/2010 9:45:16 AM

i understand what its saying just not WHAT it is saying

12/9/2010 9:57:08 AM

Lol 10-4

12/9/2010 10:06:44 AM