Quote :

"Increased Fructose Consumption May Deplete Cellular Energy in Patients with Obesity and Diabetes Obese people who consume increased amounts of fructose, a type of sugar that is found in particular in soft drinks and fruit juices, are at risk for nonalcoholic fatty liver disease (NFALD) and more its more severe forms, fatty inflammation and scarring. Nonalcoholic fatty liver disease is currently the leading cause of chronic liver disease in the United States. This condition can lead to elevated liver enzymes, inflammation and rarely even advanced scarring (cirrhosis) in individuals who do not drink alcohol. In obesity and/or diabetes, the ability of the cells to optimally make ATP may already be impaired. Unlike other simple sugars, fructose requires ATP for its metabolism. The inability to optimally generate cellular energy as well and the continued consumption of ATP from chronic fructose ingestion can result in the liver's depletion of energy. ATP depletion may increase risk for inflammation and scarring in the liver. "The state of being insulin resistant impairs the ability of a vital enzyme, AMP kinase, to make new ATP molecules," Abdelmalek explained. "Increased fructose consumption, and excess utilization of ATP favors the increase in molecules that lead to increased fatty acid synthesis as well as increased uric acid." The researchers also noted that more uric acid is produced in the body when excess fructose is consumed. Too much uric acid is associated with conditions that include gout, high blood pressure, cardiovascular disease, type 2 diabetes, metabolic syndrome and uric acid stones, a form of kidney stones."

http://www.dukehealth.org/health_library/news/increased-fructose-consumption-may-deplete-cellular-energy-in-patients-with-obesity-and-diabetes

I wonder if this just applies to processed fructose or if eating craploads of fruit would produce the same results.

5/10/2012 11:06:09 AM

i thought i saw dick health

I'm Krallum and I approved this message.

5/10/2012 11:06:46 AM

got your mind on the dick do you Krallum?

5/10/2012 11:08:19 AM

Quote :

"I wonder if this just applies to processed fructose or if eating craploads of fruit would produce the same results."

Fruit, surprisingly, is not loaded with fructose, at least not anywhere near candy or products with HFCS.

http://www.marksdailyapple.com/the-definitive-guide-to-sugar/#axzz1uTpz7dy4

5/10/2012 11:18:06 AM

Forgive my ignorance, but would this affect drinks sweetened by real sugar or is it primarily referring to those sweetened by HFCS?

5/10/2012 11:19:48 AM

^ nm apparently it's not lol.

[Edited on May 10, 2012 at 11:23 AM. Reason : a]

5/10/2012 11:21:35 AM

^strike that, reverse it.

5/10/2012 11:23:50 AM

Quote :

"Sucrose is a disaccharide sugar comprised of fructose and glucose in a 1:1 ratio. It’s perhaps the most familiar of the sugars, since sucrose is also known as table sugar. Although it’s found in fruit and other plants (often with varying amounts of free fructose), sugar cane and sugar beets are the most popular sources for commercial production. Given that sucrose contains a large amount of fructose, it shows similar metabolic patterns to the monosaccharide fructose and particularly to high fructose corn syrup, which is commonly blended to an approximate 55% fructose: 45% glucose mixture. "

So it is but it isn't. You're probably best off sticking to water and unsweetened drinks.

5/10/2012 11:25:11 AM

Quote :

"According to the USDA, HFCS consists of 24% water, and the rest sugars. The most widely used varieties of high-fructose corn syrup are: HFCS 55 (mostly used in soft drinks), approximately 55% fructose and 42% glucose; and HFCS 42 (used in beverages, processed foods, cereals and baked goods), approximately 42% fructose and 53% glucose."

Per wikipedia. So, probably no notable difference between the two in regards to this.

5/10/2012 11:28:05 AM

So if I drink alcohol it'll negate the liver problems right?

5/10/2012 11:29:30 AM

I think so. Rum + Coke = Liver Therapy.

5/10/2012 11:36:19 AM

In other news: obese people are at risk of developing [insert disease related to obesity] because they can't put down the twinkies and sodas

5/10/2012 5:14:33 PM

I'd be curious to know if this same effect can be found in people that aren't classified as obese. We all know that guy that eats cheeseburgers and Mountain Dew all day but looks like he eats nothing.

5/10/2012 5:16:14 PM

just goes to show that these commercials are horseshit: http://www.youtube.com/watch?v=Fyj2N-AspqU

which anyone who's taken a basic biology course would know

5/10/2012 5:18:25 PM

Quote :

"I'd be curious to know if this same effect can be found in people that aren't classified as obese. We all know that guy that eats cheeseburgers and Mountain Dew all day but looks like he eats nothing."

I was wondering that too. I have a buddy who will come to the lake with me and roll through 12-24 regular Mountain Dews and a suitcase of beer in a normal weekend. He buys terrible food (Little Debbie, Chips, etc.) for all his snacking and doesn't hold back on the portions at meal time yet he isn't fat at all. In bad shape with regards to strength and cardio IMO, but not more than 10-15 lbs overweight if that. And he's eaten like that for at least the past decade so it's nothing new for him.

[Edited on May 10, 2012 at 5:59 PM. Reason : s]

5/10/2012 5:58:53 PM

Quote :

"We all know that guy that eats cheeseburgers and Mountain Dew all day but looks like he eats nothing."

I'm that guy

And I can confirm that I have zero fucking energy...ever

Probably more to do with lack of exercise

5/10/2012 7:26:43 PM

I hate people like you lol.

5/10/2012 9:39:35 PM